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Pharmacy Department Università di Parma V.le P.G Usberti 27/A Campus Universitario 43100 Parma (Italy) tel: +39 0521 905062 fax: +39 0521 905006 e-mail: alessio.lodola@unipr.it |
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Pharmacy Department Università di Parma V.le P.G Usberti 27/A Campus Universitario 43100 Parma (Italy) tel: +39 0521 905062 fax: +39 0521 905006 e-mail: alessio.lodola@unipr.it |
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Dr. Lodola received his Pharm. D. in Pharmaceutical Chemistry and Technology in the academic year 2000-2001 from the Faculty of Pharmacy at the University of Parma, Italy (tutor: Prof. Mozzarelli). |
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After the degree he worked with Dr. Cozzini at the Laboratory of Molecular Modelling of the University of Parma, collaborating with Prof. Kellogg (Virginia Commonwealth University) to the development of new computational tools (e.g. scoring function) for drug discovery applications. |
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In 2002 he joined the Medicinal Chemistry Group of the University of Parma and he started the PhD with Prof.Marco Mor working at the project "Enzyme and Receptor Models in Drug Discovery". |
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In 2004, he spent 8 months at the University of Bristol (UK), in the Prof. Mulholland's group to work in the field of enzymatic reaction simulations, and in 2005 Dr. Lodola successfully completed his PhD. |
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In 2006 and 2007 Dr. Lodola has been Visitor Researcher at the Centre for Computational Chemistry of the University of Bristol. |
| In the period November 2008 - February 2009, he has been Visitor Scientist at the Drug Discovery & Development Unit (D3) of the Italian Institute of Technology (IIT) |
| Since January 2010 is a Scientific Consultant for the Drug Discovery & Development Unit (D3) of the Italian Institute of Technology (IIT) |
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Since November 1, 2005, he is Researcher (Assistant Professor) at the Faculty of Pharmacy of the University of Parma. |
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The research activities of Dr. Lodola, which have led to nearly 40 papers in peer-reviewed international journals are focused on the following research fields: 1) The endocannabinoid system, with particular emphasis on the characterization of the catalytic mechanism and inhibition of the enzyme fatty acid amide hydrolase (FAAH) and the design of FAAH inhibitors based on a carbamic structure. 2) Melatonin receptor ligands: ligand design and SAR investigations of a new class of selective MT2 receptor antagonists employing docking and molecular dynamics approaches 3) Anti-proliferative agents with particular emphasis to the design and SAR investigations of inhibitors of the EGFR receptor and of Eph-ephrin system modulators |
| Emerging investigator at the Gordon Research Conference on "Cannabinoid Function in the CNS", University of New England, Biddeford, ME, August 2-7, 2009. |
| Runner-up of the 2010 European Federation of Medicinal Chemistry (EFMC) Prize for "Young Medicinal Chemist in Academia" |
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Since the academic year 2006-2007 Dr. Lodola is encharged of the course of "Analisi dei Medicinali" (C.T.F, II° year) |