Università degli Studi di Parma
Dipartimento Farmaceutico

Research Activities

The following research subjects are active

- Analysis of structure - metabolism relationships.
- Combinatorial synthesis of Epidermal Growth Factor Receptor (EGFR) inhibitors.
- Design and QSAR of endocannabinoid system modulators.
- Design, synthesis and QSAR of histamine H3 receptor antagonists.
- Design, synthesis and QSAR of melatonin receptor ligands.
- Design, synthesis and QSAR of nuclear receptor modulators.
- Design, synthesis, structural characterization and SAR/QSAR studies of heterocyclic compounds as potential antimicrobial, antiviral, antiproliferative, anti-inflammatory, antidegenerative on cartilage, antiplatelet, and local anaesthetic agents
- Experimental determination of physico-chemical properties of drugs.
- New synthetic pathways, through phosphorous compounds, to heterocyclic intermediates useful in the preparation of derivatives of biopharmacological interest
- Studies of chemical and metabolic drug and prodrug stability.
- Synthesis, chemical and biological evaluation of heterocyclic compounds and phenylureas interesting as potential plants growth regulators