Università degli Studi di Parma
Dipartimento Farmaceutico

Scientific Production 2007

I. Scientific papers

1) P. VICINI, M. INCERTI, V. CARDILE, F. GARUFI, S. RONSISVALLE, A.M. PANICO. "Benzo[d]isothiazol-3-yl-benzamidines: a class of protective agents on culture of human cartilage and chondrocytes stimulated by IL-1ß", ChemMedChem, 2, 113-119 (2007). 

2) M.C. RODRÍGUEZ-ARGÜELLES, S.M.-VÁZQUEZ, P. TOURÓN-TOUCEDA, J. SANMARTÍN-MATALOBOS, A.M. GARCÍA-DEIBE, M. BELICCHI-FERRARI, G. PELOSI, C. PELIZZI, F. ZANI. "Complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin. A study of their antimicrobial activity", Journal of Inorganic Biochemistry, 101, 138-147 (2007)

 3) A. AMADASI, P. COZZINI, M. INCERTI, E. DUCE, E. FISICARO, P. VICINI. "Molecular modeling of binding between amidinobenzisothiazoles, with antidegenerative activity on catilage, and matrix metalloproteinase-3", Bioorganic and Medicinal Chemistry, 15, 1420-1429 (2007). 

4) A. LODOLA, M. MOR, J. ZUREK, G. TARZIA, D. PIOMELLI, J.N. HARVEY, A.J. MULHOLLAND. "Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase", Biophysical Journal: Biophysical Letters, L20-L22. 

5) V. ZULIANI, G. COCCONCELLI, M. FANTINI, C. GHIRON, M. RIVARA. "A practical synthesis of 2,4(5)-diarylimidazoles from simple building blocks", Journal of Organic Chemistry, 72, 4551-4553 (2007). 

6) S. BERTONI, L. FLAMMINI, V. MANENTI, V. BALLABENI, G. MORINI, M. COMINI, E. BAROCELLI. "In vitro pharmacology at human histamine H3 receptors and brain access of non-imidazole alkylpiperidine derivatives", Pharmacological Research, 55, 111-116 (2007).

7) A. FOPPOLI, L. ZEMA, A. GAZZANIGA, M.R. CAIRA, L.R. NASSIMBENI, E. BORKUM, R. BETTINI, F. GIORDANO. "Solid-state chemistry of amboxol theophylline-7-acetate", Journal of Pharmaceutical Sciences, 96 (5), 1139-1146 (2007). 8) C. PADULA, S. NICOLI, P. COLOMBO, P. SANTI. "Single-layer transdermal film containing lidocaine: modulation of drug release", European Journal of Pharmaceutics and Biopharmaceutics, 66, 422-428 (2007). 

9) F. ZANARDI, A. SARTORI, C. CURTI, L. BATTISTINI, G. RASSU, G. NICASTRO, G. CASIRAGHI. "Diasteroselective synthesis of 4,5'-bis-proline compounds via reductive dimerization of N-acyloxyminium ions", Journal of Organic Chemistry, 72, 1814-1817 (2007). 

10) R. RUSSO, J. LOVERME, G LA RANA, T.R. COMPTON, J. PARROTT, A. DURANTI, A. TONTINI, M. MOR, G. TARZIA, A. CALIGNANO, D. PIOMELLI. "The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neropathic pain after oral administration in mice", Journal of Pharmacology and Experimental Therapeutics, 322 (1), 236-242 (2007). 

11) S. NICOLI, P. SANTI. "Suitability of excised rabbit ear skin - fresh and frozen - for evaluating transdermal permeation of estradiol", Drug Delivery, 14, 195-199 (2007).

12) R. CORTESI, E. ESPOSITO, F. CORRADINI, E. SIVIERI, M. DRECHSLER, A. ROSSI, A. SCATTURIN, E. MENEGATTI. "Non-phospholipid vesicles as carriers for peptides and proteins: production, characterization and stability studies", International Journal of Pharmaceutics, 339, 52-60 (2007). 

13) C. PADULA, S. NICOLI, V. AVERSA, P. COLOMBO, F. FALSON, F. PIROT, P. SANTI. "Bioadhesive film for dermal and transdermal drug delivery", European Journal of Dermatology, 17 (4), 309-312 (2007). 

14) R. BETTINI, C. PEZZAROSSA, F. GIORDANO, M.R. CAIRA. "Crystal structure of midazolam saccharinate", Analytical Sciences, 23, x143-x144 (2007). 

15) G. TARZIA, F. ANTONIETTI, A. DURANTI, A. TONTINI, M. MOR, S. RIVARA, P. TRALDI, G. ASTARITA, A. KING, J.R. CLAPPER, D. PIOMELLI. "Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754)", Annali di Chimica, 97, 877-894 (2007).

16) S. PEDERSEN, F. MARRA, S. NICOLI, P. SANTI. "In vitro skin permeation and retention of parabens from cosmetic formulations", Interanational Journal of Cosmetic Sciences, 29, 361-367 (2007). 

17) C. FUNARO, G. MONDELLI, V. BELLAVIA, C. PADULA, N. GANDOLFI, R. TREBBI, R. BETTINI. "Mixing and clearing efficiency on a 200-liters perforated coating pan equipped with shark fin baffles", Tablets & Capsules, 5 (7), 20-29 (2007). 

18) M. BORTOLATO, R.A. MANGIERI, J. FU, J.H. KIM, O. ARGUELLO, A. DURANTI, A. TONTINI, M. MOR, G. TARZIA, D. PIOMELLI. "Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress", Biological Psychiatry, 62, 1103-1110 (2007).

19) R. BETTINI, A. ROMANI,  A.F. BORGHETTI. "Physicochemical and cell adhesion properties of chitosan films prepared from sugar and phosphate-containing solutions", European Journal of Pharmaceutics and Biopharmaceutics, 68, 74-81 (2008). 

20) G. SPADONI, A. BEDINI, G. DIAMANTINI, G. TARZIA, S. RIVARA, S. LORENZI, A. LODOLA, M. MOR, V. LUCINI, M. PANNACCI, A. CARONNO, F. FRASCHINI. "Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists", ChemMedChem, 2, 1741-1749 (2007). 

21) I. PASQUALI, R. BETTINI, F. GIORDANO. "Thermal behaviour of diclofenac, diclofenac sodium and sodium bicarbonate compositions", Journal of Thermal Analysis and Calorimetry, 90 (3), 903-907 (2007). 

22) G. VALITUTTI, A. DURANTI, A. LODOLA, M. MOR, G. PIERSANTI, D. PIOMELLI, S. RIVARA, A. TONTINI, G. TARZIA, P. TRALDI. "Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamate FAAH inhibitors", Journal of Mass Spectrometry, 42, 1624-1627 (2007).

III. Proceedings

1) F. BUTTINI, P. COLOMBO, C. MARRIOTT, S. JONES. "The use of vinyl polymers to enhance the aerosolisation and dissolution of budesonide from dry powder inhaler formulations", Respiratory Drug Delivery Europe 2007, Novotel Paris Tour Eiffel, Paris (France), April 17th -20th, 357-360 (2007). 

2) O.L. STRUSI, P. COLOMBO, F. SONVICO, R. BETTINI. "Dome Matrix® platform having clindamycin and artesunate innovative release for malaria oral therapy", GEA-NUS 10th Anniversary Commemorative, Pharmaceutical Technology Conference, National University of Singapore, Singapore (Singapore), December 17th-19th, 2007.

IV.Conference communications

1) A. ROMANI, M. MORGANTI A.F. BORGHETTI, R. BETTINI. "Study on physical properties and cytocompatibility of chitosan films prepared from sugar and phosphate containing solutions", International Workshop on Applications of Chitosan in Medical Sciences, Abstract pag. 45, Venice (Italy), January, 25th - 26th, 2007. (C) 

2) F. ZANI, A. GERONIKAKI, P. VERVERIS, A. ARGIROPOULOU, M. INCERTI, P. VICINI. "Synthesis and Antimicrobial Properties of Benzothiazole Benzenesulfonamides", 10th IBN SINA, International Conference on Pure and Applied Heterocyclic Chemistry, Luxor (Egypt), February 17-20, 2007. (P) 

3) S. BARBIERI, F. SONVICO, A. DERIU, P. COLOMBO. "Progesterone loading in lecithin/chitosan/isopropyl myristate nanoparticles for buccal delivery", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P) 

4) P. BARATA, O.L. STRUSI, F. SONVICO, P. COLOMBO, R. BETTINI, M.J. SOUSA LOBO, D. SANTOS, D. FERREIRA. "Humans and dogs evaluation of new gastroretentive system obtained with Dome Matrix® technology", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P) 

5) C. COMO, F. SONVICO, A. ROSSI, E. CORRADINI, P. COLOMBO. "A new nanosystem for tamoxifen citrate oral delivery", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P) 

6) C. PARLATI, F. BUTTINI, F. SONVICO, P. COLOMBO. "Preparation and in vitro evaluation of tobramycin dry powder inhaler", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P) 

7) R.P. RAFFIN, S.S. GUTERRES, F, BUTTINI, F. SONVICO, C. PARLATI, P. COLOMBO. "Chimeral agglomerates containing pantoprazole microparticles: preparation and gastro-resistence evaluation", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P)

8) O.L. STRUSI, C. CONTI, F. SONVICO, R. BETTINI, P. COLOMBO. "Dome Matrix® technology: multiple kinetics drug delivery system for time and space clindamycin phosphate controlled release", 2007 AItUN Meeting: Pharmaceutical Nanotechnology & Drug Delivery, Faculty of Pharmacy, University of Ferrara (Italy), March 9th, 2007. (P) 

9) F. BUTTINI. "Improving respirability of a budesonide dry powder using vinyl polymers", APS Inhalation 2007, University of Bath, Bath (United Kingdom), March 27th-28th, 2007. (C). 

10) F. BUTTINI, P. COLOMBO, C. MARRIOTT, S. JONES. "The use of vinyl polymers to enhance the aerosolisation and dissolution of budesonide from dry powder inhaler formulations", Respiratory Drug Delivery Europe 2007, Novotel Paris Tour Eiffel, Paris (France), April 17th-20th, 2007. (P) 

11) I. PASQUALI, L. MESSENE, R. MENABENI, M.B. PRANZO, R. TOZZI, F. GIORDANO, R. BETTINI. "Recrystallization of didanosine using a supercritical antisolvent (SAS) process", Pre-Satellite Meeting for and by Ph.D. students and postdoctoral fellows of the 3rd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC), Amsterdam (The Netherlands), April 20th-21st, 2007. (P) 

12) F. BUTTINI, P. COLOMBO, C. MARRIOTT, S. JONES. "Monitoring the modification of budesonide-lactose interactions within dry powder inhaler formulations using atomic force microscopy", 3rd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC2007), Amsterdam (The Netherlands), April 22nd-25th, 2007. (C) 

13) F. BUTTINI, R. RAFFIN, P. COLOMBO, F. SONVICO, A. POHLMANN, S. GUTERRES. "Preparation of soft agglomerates containing pantoprazole gastro-resistant microparticles", 3rd World Congress of the Board of Pharmaceutical Sciences of FIP (PSWC2007), Amsterdam (The Netherlands), April 22nd-25th, 2007. (P) 

14) R.P. RAFFIN, P. COLOMBO, F. SONVICO, F.S. POLLETO, G. COLOMBO, A. ROSSI, S.S. GUTERRES, A.R. POHLMANN. "Agglomerates containing pantoprazole gastro-resistant microparticles: formulation study", 6th International Symposium on Natural Polymers and Composites (ISNAPOL 2007), Gramado, RS (Brazil), April 22nd-25th, 2007. (P) 

15) A. PANICO, F. GARUFI, S. RONSISVALLE, G. RONSISVALLE, M. INCERTI, P. VICINI. "Synthesis and evaluation of some novel 2-heteroarylimino-4-thiazolidinones as chondroprotective agents on chondrocytes stimulated by IL-1ß, 5th Joint Meeting on Medicinal Chemistry, Portorož (Slovenia), June 17th-21st, 2007. (P) 

16) F. ZANI, F. BESAGNI, A. GERONIKAKI, M. INCERTI, P. VICINI. "Synthesis and antimicrobial activity of some 2-benzenesulfonamidothiazoles", 5th Joint Meeting on Medicinal Chemistry, Portorož (Slovenia), June 17th-21st, 2007. (P) 

17) A.G. BALDUCCI, A. ROSSI, F. SONVICO, P. COLOMBO. "Gastro-resistant microparticles of mesalazine for pediatric administration", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

18) M.B. PRANZO, M. CORUZZI, R. BETTINI. "Interaction between albendazole and nicotinammide in the solid state and in solution", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

19) R. TOZZI, R. MENABENI, I. PASQUALI, M.R. CHIEROTTI, R. GOBETTO, R. BETTINI. "Soldi-state characterization of didanosine crystallized with a supercritical antisolvent process", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

20) C. PARLATI, F. BUTTINI, F. SONVICO, P. COLOMBO. "Tobramycin dry powder for inhalation", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

21) O.L. STRUSI, F. SONVICO, R. BETTINI, P. COLOMBO. "Multiple kinetics delivery system for time and space clindamycin controller release", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

22) B. VIETTI, P. SANTI. "Effect of ionization and lipophilicity on permeation of model molecules through urinary bladder epithelium", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

23) I. PASQUALI, F. PUCCIARELLI, J.M. ANDANSON, S.G. KAZARIAN, R. BETTINI. "Study of the ternary system PEG 1500/supercritical CO2/diazepam", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

24) I. PASQUALI, L. MESSENE, R. MENABENI, M.B. PRANZO, R. TOZZI, R. BETTINI. "Recrystallization of didanosine using a supercritical antisolvent (SAS) process", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P)

25) E. DALLATURCA, M. RIVARA, V. ZULIANI, M. MOR, F. BORDI. "Synthesis of new non-imidazole histamine H3 receptor antagonists by microwave technology", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

26) A. FIONI, F. VACONDIO, M. MOR, C. SILVA, A. LODOLA, S. RIVARA, A. DURANTI, A. TONTINI, G. TARZIA, D. PIOMELLI. "Chemical and biological stability of a class of carbamates inhibiting FAAH: structure-property relationships", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P) 

27) M. FANTINI, S. LORENZI, F. BERNINI, F. BORDI, M. MOR. "Synthesis of potential LXR agonists", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. (P)

28) A. GERONIKAKI, P.T. ELEFTHERIOU, C. PETROU, P. VICINI. "Novel 2-amino-5-benzylidenethiazol-4-one derivatives with SHP-2 inhibitory action. Potent drugs for the treatment patients with noonan syndrome and high tendency for leukemia", 6th AFMC International Medicinal Chemistry Symposium, Istanbul (Turkey), July 8th-11th, 2007. (P) 

29) C. COMO, F. SONVICO, A. ROSSI, S. MOTTA, P. COLOMBO. "A new nanosystem for tamoxifen citrate oral delivery", 16th International Symposium on Microencapsulation, Lexington, Kentucky (USA), September 9th-12th, 2007. (P) 

30) C. PARLATI, F. BUTTINI, F. SONVICO, P. COLOMBO. "Innovative tobramycin dry powder for pulmonary administration", 16th International Symposium on Microencapsulation, Lexington, Kentucky (USA), September 9th-12th, 2007. (P) 

31) G. COLOMBO, F. BORTOLOTTI, P. COLOMBO, E. MENEGATTI, F. SONVICO. "Soft agglomerates containing microincapsulated levothyroxine for buccal or oral delivery", 16th International Symposium on Microencapsulation, Lexington, Kentucky (USA), September 9th-12th, 2007. (P) 

32) S. RIVARA, M. MOR, S. LORENZI, G. SPADONI, A. BEDINI, G. TARZIA, V. LUCINI, F. FRASCHINI, G. GOBBI. "Novel anti-anxiety and sleep-promoting melatonin receptor ligands from modulation of N-anilinoethylamide structure", 16th Camerino-Noordwijkerhout Symposium, An Overview of Receptor Chemistry, Camerino (Italy), September 9th-13th, 2007. (C) 

33) I. PASQUALI, F. PUCCIARELLI, J.M. ANDANSON, S.G. KAZARIAN, R. BETTINI. "Diazepam/PEG 1500 phase behaviour under supercritical CO2", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (C) 

34) P. COELHO, O.L. STRUSI, F. SONVICO, R. BETTINI, P. COLOMBO, L. RIBEIRO, D. SANTOS, J.M. SOUSA LOBO, D. FERREIRA. "Gastric retention and bioavailability determination of ranitidine immediate and controller release dome matrix formulations in dogs", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (C) 

35) F. MARRA, C. OSTACOLO, C. PADULA, S. LANERI, A. SACCHI, P. SANTI. "Synthesis and skin permeation of aminoacidic esters of a-tocopherol", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

36) C. PADULA, N. CAMPANA, P. SANTI. "Benzophenone-3 and retinyl acetate skin permeation and accumulation", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

37) S. NICOLI, C. PADULA, B. VIETTI, A. MILLET, F. FALSON, P. SANTI. "Characterization of rabbit ear skin as a skin model for in vitro transdermal permeation experiments: histology, lipid composition and permeability", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

38) R. CORETSI, E. ESPOSITO, M. DRECHSLER, A. ROSSI, E. MENEGATTI. "Non-ionic surfactant vesicles to carry peptides and proteins", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

39) F. SONVICO, S. BARBIERI, A. ROSSI, Y. GERELLI, A. DERIU, P. COLOMBO, G. COLOMBO. "Progesterone-loaded lecithin/chitosan/isopropyl myristate nanoparticles for transmucosal delivery", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

40) R.P. RAFFIN, P. COLOMBO, A. ROSSI, L.M. COLOMÉ, D.S. JORNADA, A.R. POHLMANN, S.S. GUTERRES. "Enteric microparticles containing pantoprazole: stability study and in vivo activity", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

41) P. RUSSO, F. SANSONE, M. PESCA, P. DEL GAUDIO, P. COLOMBO, R.P. AQUINO. "Innovative dry powder formulations of flavonoide for pulmonary administration in cystic fibrosis patients", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

42) F. BUTTINI, P. COLOMBO, C. MARRIOTT, S. JONES. "The study of the drug-carrier interaction in dry powder inhaler formulations using the atomic force microscope", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

43) G. COLOMBO, P. RUSSO, F. SONVICO, E. HESSE, L. FERRARO, F. BORTOLOTTI, P. COLOMBO. "Desmopressin dry powder for nasal administration", 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007. (P) 

44) A. LODOLA, M. MOR, S. RIVARA, A. DURANTI, A. TONTINI, G. TARZIA, D. PIOMELLI. "QSAR and molecular modelling investigations of a new series of alkyl carbamic acid biphenyl-3-yl ester inhibitors of fatty acid amide hydrolase", Frontiers in CNS and Oncology Medicinal Chemistry, Siena (Italy), October 7th-9th, 2007. (P)

 45) R. OCHOA-SANCHEZ, G. COHEN, G. SPADONI, A. BEDINI, M. MOR, S. RIVARA, F. FRASCHINI, G. TARZIA, G. GOBBI. "Selective increase of Slow Wave Sleep (SWS) by a novel melatonin partial agonist", Neuroscience 2007, 735.22/UU9, San Diego, California (USA), November 3rd-7th, 2007. (P) 

46) A.R. KING, A. ROSENGARTH, J. CLAPPER, A. DURANTI, A. TONTINI, M. MOR, S. RIVARA, G. TARZIA, D. PIOMELLI. "Characterization of the monoacylglycerol lipase (MGL) inhibitor URB602", Neuroscience 2007, 244.4/G16, San Diego, California (USA), November 3rd-7th, 2007. (P) 

47) I. PASQUALI, J.M. ANDANSON, S. KAZARIAN, R. BETTINI. "PEG 1500/diazepam phase behaviour under supercritical CO2 by ATR-IR spectroscopy", 2007 AAPS Annual Meeting, n° W4375, San Diego, California (USA), November 11th-15th, 2007. (P) 

48) R. BETTINI, R. MENABENI, I. PASQUALI, R. TOZZI, M.R. CHIEROTTI, R. GOBETTO. "Solid-state characterization of didanosine crystallized with a supercritical antisolvent process", 2007 AAPS Annual Meeting, n° W4253, San Diego, California (USA), November 11th-15th, 2007. (P) 

49) F. BERTOLINI, C. CAMELLINI, L. ARDUINI, R. BETTINI. "New rumen-resistant microencapsulated choline chloride pellets", 2007 AAPS Annual Meeting, n° T2055, San Diego, California (USA), November 11th-15th, 2007. (P) 

50) O.L. STRUSI, F. SONVICO, A. ROSSI, R. BETTINI, G. MAJORI, P. COLOMBO. "Clindamycin-artesunate combined multi-kinetics drug delivery system for malaria therapy", 2007 AAPS Annual Meeting, San Diego, California (USA), November 11th-15th, 2007. (P) 

51) F. BUTTINI, A. VITALE, A. ROSSI, F. SONVICO, P. COLOMBO. "High respirable insulin dry powder for pulmonary administration", 2007 AAPS Annual Meeting, San Diego, California (USA), November 11th-15th, 2007. (P) 

52) C. COMO, F. SONVICO, A. ROSSI, E. CORRADINI, P. COLOMBO. "Lecithin/chitosan based nanosystem for tamoxifen citrate oral delivery", 2007 AAPS Annual Meeting, San Diego, California (USA), November 11th-15th, 2007. (P) 

53) R.P. RAFFIN, P. COLOMBO, F. SONVICO, A. ROSSI, A. POHLMANN, S. GUTERRES. "Preparation and characterization of a pantoprazole new drug delivery system for oral administration based on soft agglomerates", 2007 AAPS Annual Meeting, San Diego, California (USA), November 11th-15th, 2007. (P) 

54) F. SONVICO, G. COLOMBO, L. GALLINA, F. BORTOLOTTI, P. COLOMBO, E. MENEGATTI, A. SCAGLIARINI. "Use of sucralfate gel as a vehicle for topical administration of the antiviral drug cidofovir", 2007 AAPS Annual Meeting, San Diego, California (USA), November 11th-15th, 2007. (P)

55) O.L. STRUSI. "Dome Matrix®: a new platform for oral drug delivery", 47° Simposio AFI, Rimini, 13-15 Giugno 2007. (C) 

56) F. BUTTINI, S. CAGNANI, C. PARLATI, A. VITALE, F. SONVICO, P. COLOMBO. "Polveri secche di insulina per somministrazione polmonare", 47° Simposio AFI, Rimini, 13-15 Giugno 2007. (P) 

57) G. SPADONI, A. BEDINI, G. TARZIA, M. MOR, S. RIVARA, V. LUCINI, F. FRASCHINI, G. GOBBI. "N-(anilinoethyl)acylamides: new melatonin receptor ligands with sleep inducing properties", XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana, Facoltà di Farmacia, Università G. D'Annunzio di Chieti-Pescara, Chieti, 16-20 Settembre 2007. (C) 

58) A. TONTINI, A. KING, J. CLAPPER, A. DURANTI, A. LODOLA, M. MOR, S. RIVARA, A. ROSENGARTH, G. TARZIA, D. PIOMELLI. "Synthesis and biological activity of monoacylglycerol lipase (MGL) inhibitor URB602 and its analogs", XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana, Facoltà di Farmacia, Università G. D'Annunzio di Chieti-Pescara, Chieti, 16-20 Settembre 2007. (P)

V. Invited speakers

1) P. COLOMBO. "Internationalization activities and progress towards the European Credit Transfer System", One Day Seminar The EU-Asean Credit Transfer System (EACTS), Faculty of Engineering, University of Parma, Parma (Italy), February 21st, 2007. 

2) P. COLOMBO. "Encapsulation of pharmaceuticals and drug delivery technologies", Preliminary program for Packaging Tour, STFI-Packforsk, Stockholm (Sweden), March 29th-30th, 2007. 

3) P. COLOMBO. "Dome Matrix®: a new technology for flexible oral drug delivery control", LACDR Spring Symposium, University of Amsterdam (The Netherland), April 4th, 2007. 

4) P. COLOMBO. "Particle technology for pulmonary delivery of insulin", Advances in Drug Delivery for Inhalation, University of Milan, Milan (Italy), April 23rd, 2007. 

5) P. COLOMBO. "Dome Matrix®: a new technology for flexible oral drug delivery control", Seminar, Department of Pharmacy, University of Uppsala, Uppsala (Sweden), May 10th, 2007. 

6) R. BETTINI. "Innovative health products", The challenge of biotechnologies, Primavera Italiana in Giappone, Osaka (Japan), May 15th, 2007. 

7) M. MOR, A. LODOLA. "Molecular modelling and quantitative SAR", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. 

8) P. COLOMBO, P. SANTI, A. ROSSI, F. SONVICO. "Oral, inhalation and transdermal drug delivery systems", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. 

9) J. BOUWSTRA, P. SANTI. "Drug delivery across the skin", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. 10) P. COLOMBO. "Dome Matrix®: A new platform for oral drug delivery", 8th ULLA Summer School, Leiden (The Netherlands), June 29th-July 7th, 2007. 

10) P. COLOMBO. "Chimeral agglomerates for nasal or buccal delivery", Seminar, University of Nagoya, Nagoya (Japan), July 23rd, 2007. 12) P. COLOMBO. "Dome Matrix®: a new technology for flexible oral drug delivery control", Seminar, University of Tokyo, Tokyo (Japan), July 27th, 2007. 

11) P. COLOMBO. "Dome Matrix® technology for oral drug delivery control in time and space", The 5th International Postgraduate Research Symposium on Pharmaceutics, Istanbul (Turkey), September 13th-15th, 2007. 

12) M. MOR. "Fatty acid amide catabolism and chemical approaches to its inhibition", 3rd International Meeting on Medicinal and Pharmaceutical Chemistry, WOW Kremlin Palace, Antalya (Turkey), October 16th-21st, 2007. 

13) R. BETTINI. "Nettoyage en place (CIP) de machines pour les formes solides", IMA CIP Day, Seminaire sur les dispositifs de nettoyage en place, Ozzano Emilia (Italy), November, 21st, 2007.

14) R. BETTINI. "Particle and crystal engineering mediante fluidi supercritici", Workshop su Polimorfismo dei farmaci: fondamenti e innovazione, Bologna, 1-2 Febbraio 2007. 

15) P. COLOMBO. "Insulina polmonare: tecnologia delle particelle per la somministrazione inalatoria", Convegno Sviluppo di farmaci biotecnologici, Univeristà di Pavia, Collegio Volta, Pavia, 7-8 Marzo 2007. 

16) R. BETTINI. "Validation of C.I.P. system: Perfima and Ghibli", IMA CIP Day, Ozzano Emilia (BO), 5 Aprile 2007. 

17) A. ROSSI. "DSC: Metodiche di Base", Seminario, Dipartimento di Scienze Farmaceutiche dell'Università degli Studi di Salerno, Fisciano (SA), 18 Aprile 2007. 

18) A. ROSSI. "DSC: Applicazioni in campo Farmaceutico", Seminario presso il Dipartimento di Scienze Farmaceutiche dell'Università degli Studi di Salerno, Fisciano (SA), 18 Aprile 2007. 

19) A. ROSSI. "Corso pratico di corretto utilizzo dello strumento DSC", Seminario, Dipartimento di Scienze Farmaceutiche dell'Università degli Studi di Salerno, Fisciano (SA), 18 Aprile 2007. 

20) R. BETTINI. "Il Consorzio TEFARCO come interfaccia fra università e aziende", Conferenza ISPE Le aziende incontrano le università e gli enti di controllo, Milano, 5 Luglio 2007. 

21) R. BETTINI. "Estrazione e formulazione di fitocomplessi con CO2 supercritica", 7a Scuola Dottorale per la Formazione Avanzata in Discipline Tecnologico Farmaceutiche, Arcavacata di Rende, 10 Settembre 2007.

VI. Chairperson

1) R. BETTINI. International Workshop on Applications of Chitosan in Medical Sciences, Venice (Italy), January, 25th-26th, 2007.

2) P. COLOMBO. 1st Conference on Innovation in Drug Delivery: From Biomaterials to Devices, Naples (Italy), September 30th-October 3rd, 2007.

VII. Awards

1) O.L. STRUSI. Miglior articolo scientifico "Estudios de liberación de propanolol desde matrices hidrofílicas poliectrolito. Fármaco utilizzando tecnología dome matriz", XI Congreso de la Federación Farmacéutica Sudamericana, 6to. Congreso Nacional Farmacéutico, Asunción (Paraguay), August, 2007. 

2) P. COLOMBO. Premio 2007 Rainer Hoffman Product Through Science Award per l'invenzione della tecnologia "Geomatrix®", 34th CRS Annual Meeting & Exposition, Long Beach, California (USA), July 9th, 2007. 

3) P. COLOMBO. Nomina ad esperto europeo per la valutazione di farmaci, EMEA, November 13th, 2007.

VIII. Visiting researchers

1) Prof. CHRISTOPHER MARRIOTT, London (United Kingdom), Head of Department of Pharmacy, King's College, Univeristy of London, March 22nd, 2007. 

2) Dr. MEL KOCH, Seattle, Washington (USA), Director of the Center for Process Analytical Technology (CPAC), University of Washington, March 28th, 2007. 

3) Prof. MINO RODOLFO CAIRA, Cape Town (South Africa), Department of Chemistry, University of Cape Town, April 11th, 2007. 

4) Dr. JOSÈ MARIA BERMUDEZ, Buenos Aires (Argentina), University of Buenos Aires, May 15th-June 13th, 2007. 

5) Prof. MICHELE VITOLO, São Paulo (Brazil), Pharmaceutical Biotechnology and Industrial Enzymology, University of São Paulo, May 22nd, 2007. 

6) Dr. PAOLO GUIDETTI, Baltimore, Maryland (USA), Maryland Psychiatric Research Center, School of Medicine, University of Maryland, May 25th, 2007. 

7) Dr. DANIELE RIBEIRO DE ARAUJO, Campinas (Brazil), Department of Biochemistry, State University of Campinas, June 1st-December 31st, 2007. 

8) Prof. MARC EEMAN, Gembloux (Belgium), Department of Industrial Biological Chemistry, Agricultural University, July, 20th, 2007. 

9) Prof. BART J. DE HAAN, Groningen (The Netherlands), Department of Pathology & Laboratory Medicine, Faculty of Medical Sciences, University of Groningen, November, 8th, 2007.

IX. Visiting students

1) MARTA CASAS, Universidad de Sevilla (España), September 1st-December 21nd, 2007. 

2) CRISTINA BALAQUEZ FERNANDEZ, Departamento de Fisiologia, Farmacologia y Toxicologia, Facultade de ciencias experimentals y de la salud, Universidad del Cardenal Herrera, Moncada, Valencia (España), February 5th, May 10th, 2007

X. Visiting students Program Socrates/Erasmus

1) CERNECKYTE Jeva, Kaunas University of Medicine (Lietuva), March - July, 2007. 

2) MAJAUSKAITE Tomadella, Kaunas University of Medicine (Lietuva), October 2006 - June 2007. 

3) CONCEICAO Ana Isabel, Universidade Fernando Pessoa (Portugal), March - July, 2007. 

4) SERRA SILVA LENTE CRUJEIRA Sofia, Universidade Fernando Pessoa (Portugal), March - July, 2007.

 5) CUNHA Rita, Universidade Fernando Pessoa (Portugal), September - December, 2007.

6) CARDOSO Maria João, Universidade Fernando Pessoa (Portugal), September - December, 2007. 

7) COSTA GONZALEZ Marta, Universidad de Sevilla (España), October 2006 - June 2007. 

8) FERNANDEZ-ESCADON NOSTI Victoria, Universidad de Sevilla (España), October 2006 - June 2007. 

9) CRIADO MARTINEZ Isabel, Universidad de Granada (España), October 2006 - June 2007. 

10) VILLAR VALDIZAN Maria Dolores, Universidad de Granada (España), October 2006 - June 2007. 

11) MANDAY RODRIGUEZ-RUBIO Maria Europa, Universidad de Granada (España), October 2006 - June 2007. 

12) RODRIGUEZ BARAHONA M. Conception, Universidad Alfonso X El Sabio, Madrid (España), October 2006 - June 2007. 

13) GARCIA VALENTE Paloma, Universidad Alfonso X El Sabio, Madrid (España), October 2006 - June 2007. 

14) FERNANDEZ-PENA GARCIA Teresa, Universidad Alfonso X El Sabio, Madrid (España), October 2006 - June 2007. 

15) FAGES SAEZ Angela, Universidad Alfonso X El Sabio, Madrid (España), October 2006 - June 2007. 

16) LUCAS TORREJIMENO Rocio, Universidad Complutense de Madrid (España), October 2006 - June 2007. 

17) GUYENNET Frederique, Université Claude Bernard Lyon 1 (France), October 2006 - June 2007. 

18) VAKIRTZI Vasiliki, Università Aristotele di Salonicco (Ellada), March - June 2007. 

19) ZIKOU Vaia, Università Aristotele di Salonicco (Ellada), March - June 2007. 

20) STATHOGIANNIS Maria, Università di Atene (Ellada), October 2006 - April 2007. 

21) IONNIDOU Vasiliki, Università di Atene (Ellada), March - June, 2007.

22) CIANCIO Melissa, Università di Liegi (Belgique), September - December, 2007

XI. Teacher's mobility Program Socrates/Erasmus

XII. Patents

1) G. CASIRAGHI, C. SCOLASTICO, F. ZANARDI, L. BATTISTINI, C. CURTI, G. RASSU, L. AUZZAS, P. BURREDDU, L.P. MANZONI. "Integrin targeted cyclopeptide ligands, their preparation and use", domanda PCT n° 07003540.7 del 21 Febbraio 2007, titolare Università degli Studi di Milano.

2) R.P. RAFFIN, P. COLOMBO, F. SONVICO, G. COLOMBO, A. ROSSI, F. BUTTINI. "Compositions in powder form made of soft agglomerates of a micronized drug and of a two-components excipient, and process for their preparation", PCT/EP2007/061559, 26 Ottobre 2007, titolare Università degli Studi di Parma.